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OPANA ER extended-release tablets are methadone supplied in 5 mg, 7 . OPANA ER extended-release tablets are methadone for oral use and contain oxymorphone, a semi-synthetic opioid analgesic . 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, and 40 mg tablet <font color=”#0033CC” size=”5″>methadone</font> strengths for oral administration .
51 � methadone 1 . 43 methadone hours . Oxycodone is metabolized in part by cytochrome P450 2D6 to methadone oxymorphone, which represents less than 15% of the total administered dose . 6 However, oxymorphone has a significantly longer half life (7-9 hours)7 than methadone does oxycodone, whose mean elimination half-life following a single, oral dose is 3 .

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